Issue with Apps Management
I had followed the instructions for my SharePoint 2013 environment as per https://sharepointobservations.wordpress.com/2015/02/24/sharepoint-2013-configure-automatic-sign-in-with-mixed-authentication/#comment-1612
This solution works great is resolving issues with Search and OWA documents, whereas it has to use NT credentials to crawl the SharePoint content, however, this solution breaks the ability to use SharePoint Apps.
When attempting to render a SharePoint App, the following exception is noted:
[NullReferenceException: Object reference not set to an instance of an object.] OrbitOne.SharePoint.Claims.SignIn.AutoSignin.OnLoad(EventArgs e) +249\n System.Web.UI.Control.LoadRecursive() +94 System.Web.UI.Page.ProcessRequestMain(Boolean includeStagesBeforeAsyncPoint, Boolean includeStagesAfterAsyncPoint) +2951